Spontaneously Hypertensive (SHR) Rat

SHR/NCrl
Inbred

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SHR Rat
Breeding Location

Spontaneously Hypertensive (SHR) Rat Details

Okamoto, Kyoto School of Medicine, 1963, from outbred Wistar Kyoto male with marked elevation of blood pressure mated to female with slightly elevated blood pressure. Brother x sister mating with continued selection for spontaneous hypertension was then started. To NIH in 1966 from Okamoto at F13. To Charles River from NIH in 1973 at F32.

Coat Color
White (albino)
MHC Haplotype
RT1k
Strain Code
007
Ideal For
genetic hypertension, hypertensive drug research, ADHD model, safety and efficacy testing

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